Pandemic Prevention Starts with Finding COVID-19's Root Cause
- More than six years after the COVID-19 outbreak began, its origin remains unresolved, leaving an important question about which risks pandemic prevention efforts need to address
- Bill Gurley argues that major catastrophes such as Challenger, Fukushima and the Boeing 737 MAX crashes received extensive root-cause investigations that offer a model for examining COVID-19's origins
- The CAPA framework follows five steps — detect, investigate, confirm the root cause, correct and prevent — because effective safeguards depend on knowing what produced the original failure
- The DEFUSE proposal described plans to insert a furin cleavage site into a bat coronavirus, a feature also found in SARS-CoV-2, making it an important investigative lead but not proof of a lab origin
- You can apply root-cause thinking to health and everyday decisions by separating evidence from interpretation, checking original sources, considering conflicts of interest and directing solutions at the underlying cause
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