Podcast # 483: Dual Antiplatelet Therapy in TIA

Contributor: Don Stader, MD

Educational Pearls:

• Antiplatelets include aspirin and clopidogrel, and are generally used for arterial clotting (MI, stroke)
• Anticoagulants such as coumadin, Xarelto, Eliquis are generally used for venous clotting (DVT/PE)
• Growing data suggests that dual antiplatelet therapy (aspirin+clopidogrel) is superior to aspirin alone in reducing stroke for diagnosed with TIA

References:

Kheiri B, Osman M, Abdalla A, Haykal T, Swaid B, Ahmed S, Chahine A, Hassan M, Bachuwa G, Al Qasmi M, Bhatt DL. Clopidogrel and aspirin after ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis of randomized clinical trials. J Thromb Thrombolysis. 2019 Feb;47(2):233-247. doi: 10.1007/s11239-018-1786-z. PubMed PMID: 30511260.

Summarized by Will Dewispelaere, MS4 | Edited by Erik Verzemnieks, MD