FAMILIAR FOES: 49ers Visit Texans and Old Friend DeMeco Ryans in Defensive Battle

John Hickman and Brian Peacock break down the key factors that could decide the game, like the 49ers' ability to overcome injuries, the Texans' impressive defense, and the impact of Mac Jones filling in for Brock Purdy. C.J. Stroud's challenges behind a struggling OL, and offer their predictions for what could be a low-scoring affair.