Bills vs. 49ers first look: Not same old CMC + why James Cook could be problem for SF

Matt Parrino is joined by Matt Barrows from The Athletic to preview Bills vs. 49ers from the opponents' side. Barrows covers the 49ers and takes us into what's going on with the underperforming defending NFC champs, the injury outlook for a few key starters and more. Come out on Saturday, Nov. 30 on the night before Bills-49ers for a live episode of the "SHOUT!" podcast from Turning Stone Resort Casino and the amazing NY Rec & Social Club. The guys will be hanging out from 6 pm - 10 pm. Enjoy great food, drinks and Bills talk. RSVP here: https://www.facebook.com/share/19TMknhQ9n/ What is the "SHOUT!" Bills text insiders? Want to join? You can get analysis from Matt and Ryan right to your phone and send texts directly to them both! Text 716-528-6727 or Click here: https://joinsubtext.com/shoutbuffalobills Sign up for the NYUP Bills newsletter! Don't miss all the Bills coverage. Head over to www.Syracuse.com/newsletters to start getting your Bills stories and the podcast delivered right to your inbox. SHOUT!" Buffalo Bills football podcast is available on Apple, Spotify, Google, Stitcher, and wherever you listen to podcasts Follow @MattParrino (https://twitter.com/MattParrino) and @RyanTalbotBills (https://twitter.com/RyanTalbotBills) on Twitter Find our Bills coverage whenever you like to consume social media Instagram: https://www.instagram.com/buffalobillsnyup/ Facebook: https://www.facebook.com/buffalobillsnyup X: https://x.com/billsupdates Learn more about your ad choices. Visit megaphone.fm/adchoices