Is Oregon the biggest Ohio State regular-season game (non-Michigan version) of the Ryan Day era?

Ohio State is wounded but not dead. Oregon is wounded but also maybe not dead. These two teams were ranked No. 1 and No. 2 in the preseason and will face off in Ohio Stadium on Saturday with a combined five losses. Does that make this the biggest regular-season game for Ohio State (not counting Michigan games) in the eight years of Ryan Day as the head coach?