TWiV 370: Ten out of 15

Hosts: Vincent Racaniello , Alan Dove , and Kathy Spindler The TWiVomics review ten captivating virology stories from 2015. Ten virology stories from 2015 Recoding to make vaccines and study viral functions: TWiV 351: The dengue code TWiV 362: Gotta catch ’em all and n ew paper Defining the virome: TWiV 365: Blood, feuds, and a foodborne disease , TWiV 362: Gotta catch ’em all , TWiV 356: Got viruses? , TWiV 355: Baby’s first virome , TWiV 342: Public epitope #1 , TWiV 323: A skid loader full of viromes Ebola outbreak wanes, vaccines tested, persistence noted: TWiV 361: Zombie viruses on the loose , TWiV 349: One ring to vaccinate them all , TWiV 341: Ebolavirus experiences , TWiV 336: Brought to you by the letters H, N, P, and Eye , TWiV 335: Ebola lite Spillovers and scares: TWiV 347: Rose rosette and squirrel roulette , TWiV 351: The dengue code , TWiV 364: It’s not SARS 2.0 , TWiV 365: Blood, feuds, and a foodborne disease The “Gain of Function” debate continues: TWiV 321: aTrip and a pause , TWiV 351: The dengue code , TWiV 354: The cat in the HAART , TWiV 363: Eat flu and dyad , and the NSABB’s new draft report Detailed mechanisms of pathogenesis: TWiV 336: Brought to you by the letters H, N, P, and eye , and TWiV 345: How a vaccine got the nod - plus numerous episodes (324, 328, 329, 330, 339, 343, 349, 353, 369) where we talked about basic research that undergirds these clinically important discoveries. Dengue vaccines: Trial TWiV 319: Breaking breakbone. Dengvaxia was licensed in December in Mexico, Philippines, and Brazil (12/28); paper we didn’t have time to cover about broadly neutralizing Abs from viremic patients and another paper from same group with X-ray crystal structure of Ab + gpE. Why do some RNA viruses undergo antigenic variation and others do not? TWiV 340: No shift, measles TWiV 346: A double helical career TWiV 345: How a vaccine got the nod Letters read on TWiV 370 This episode is sponsored by ASM Microbe and ASM Biodefense Weekly Science Picks Alan - Scientifics online Vincent - Giant squid in Tokyo Harbor Kathy - A Year of Sky Listener Picks Daniel - Paper Life Stephen - How to deal with science denialists Venkat - Kabisa Send your virology questions and comments to [email protected]