Total Bases | Beat the Books! Your Daily MLB Betting Fix - Predictions & Best Bets for September 22

Looking for the best MLB picks, predictions, and betting tips for Monday, September 22, 2025? Tune in to Total Bases with expert handicappers Adam Trigger, Bryan Leonard and Tokyo Brandon as they break down today’s MLB matchups with sharp insights and actionable advice. 00:00 Introduction 01:14 Seattle Mariners vs. Houston Astros 06:01 Use paid sites? 15:26 Milwaukee Brewers vs. San Diego Padres 26:01 St. Louis Cardinals vs. San Francisco Giants 35:13 What happened to the Detroit Tigers? 52:15 Future bets 57:08 Who wins the World Series? 1:00:31 Parlay of the day